My MILs anxiety levels have been increasing over the last three years till they were off the scale, she has been on a 50mg sertraline tablet for something like the last two years. I spoke to the gp a few weeks ago & he upped it to a 100mg tablet. She has now been on it just over a week & my OH went to see her yesterday & he said it was the best visit he has had in years. I see her almost daily & had noticed that she seemed a fair bit calmer but she does tend to behave differently for her son than she does for me. The confusion & repetition are just the same of course but don't seem to bother her as much.