I am new to the group so hello to every one, can anyone offer any suggestions My wife was diagnosed with Alzheimer’s approx 3 years ago and was placed on Donepezil 10mg she has been fine, but I have noticed a deterioration in her memory, ability to undertake any chores in and around the house, and lack of interest in any outside activities Doctor’s tall me no other medication other than the Donepezil which is clearly beginning to loose its effectiveness, Can anyone offer a suggestion ?