Hi All, My wife has had Alzheimers for about 5 years,she is on 10mg of Memantine per day.She is almost always tired out,we tried halving the dose of Memantine to 5 mg to see if this would reduce the tiredness (it did not) She will not let me stop the Memantine completley. I have read about Alzheimers fatigue and the side effects of Memantine (tiredness) but I have no idea which one is the problem or what to do if I knew. Most days she cannot get out of the chair and rtemains in her night clothes the whole day.She hes lost her short term memory but she is still the wife I know,It is bad enough having Alzheimers without having the extreme fatigue as well,can anyone help with advice if they have experienced this with their loved one?