My wife fell from bed the other night and fractured her clavicle. It is obviously causing her pain but since the incident her behavior has changed and is far worse than before the accident. She is taking paracetamol for the pain and her usual three times a day batch of tablets which she has just started for the first time to refuse. She just purses her lips and refuses to even acknowledge that they are there for taking. I coaxed her to put open her mouth so as to place one of the tablets on her tongue and she took the opportunity to bite my thumb very hard. After almost 30 minutes I managed to persuade her to take them but am concerned and convinced that this is part of her new behavioral pattern. Any suggestions please would be appreciated.