Hi @Linsac, sorry to read your troubles, did the sample actually show an infection? Obviously UTI's do cause havoc but if your mum lives alone then this could just be a progression of her illness. My mum was in a terrible state when she lived alone, panic, aggression, constant anxiety, phone calls at all hrs etc. The world must become a terrifying place for our Pwd when there is no one there to help them navigate through the day. I moved in with her two years ago and she immediately dropped back to her old confused but calmer self. The Alz has progressed, but it's steady and slow so far. I do find if I leave her too long unattended she can quite rapidly work herself into a state over the simplest actions, ie putting her shoes on. Wishing you and your mum well