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Two existing drugs can block cell death in mice with neurodegeneration

Discussion in 'Alzheimer's Society news' started by Alzheimer's Society, Apr 20, 2017.

  1. Alzheimer's Society

    Alzheimer's Society Volunteer Moderator

    A new study shows that two drugs can block the death of brain cells in mice.

    More...
     
  2. Hamster Wheel

    Hamster Wheel Registered User

    Apr 20, 2017
    60
    Derbyshire
    Good news for mice and their carers then.:rolleyes:
     
  3. oilovlam

    oilovlam Registered User

    Aug 2, 2015
    388
    South East
    Just saw this in an article on the BBC. The drugs are about to be trialed.

    "As one of the drugs is already available as a treatment for depression, the time taken to get from the lab to the pharmacy could be dramatically reduced."

    Seems that the drugs are Trazodone & DBM.

    Trazodone is an existing drug used for depression

    DBM must be the new compound.

    They are hoping that taken in combination it 'could' be significant.

    Let us pray that they succeed & soon. I think if the trials prove the drugs are effective then they will fast track development....but they have to make sure they are safe.

    I wonder if taking Trazodone on its own is worth considering?
     
  4. tangled89

    tangled89 Registered User

    Sep 24, 2017
    23
    I've tried had no effect
     
  5. lubyloo

    lubyloo Registered User

    Feb 9, 2015
    58
    Female
    Worc's
    Oh please, please, please, hurry with these trials so very badly needed.
     
  6. kassy

    kassy Registered User

    Dec 9, 2009
    11,859
    Poor mice,shouldn't be used.
     
  7. LadyA

    LadyA Volunteer Host

    Oct 19, 2009
    13,092
    Ireland
    Liquorice?! Wouldn't you wonder who thought to themselves "hmm. I wonder if I combined this antidepressant drug with liquorice, would it have any effect on dementia?"!! :confused:
     
  8. Lawson58

    Lawson58 Registered User

    So does all this mean that the price of liquorice is going to skyrocket? And shall we find vitamin companies will soon be marketing a new 'wonder' drug to add to all the others on the shelves?
     
  9. la lucia

    la lucia Registered User

    Jul 3, 2011
    473
    Thanks for making me giggle... Spot on! :D
     
  10. Dogma

    Dogma New member

    Nov 8, 2017
    7
    "As one of the drugs is already available as a treatment for depression, the time taken to get from the lab to the pharmacy could be dramatically reduced."

    Seems that the drugs are Trazodone & DBM.

    Trazodone is an existing drug used for depression

    DBM must be the new compound.

    They are hoping that taken in combination it 'could' be significant.

    Let us pray that they succeed & soon. I think if the trials prove the drugs are effective then they will fast track development....but they have to make sure they are safe.

    I wonder if taking Trazodone on its own is worth considering?[/QUOTE]

    Found that Trazadone is recommended for insomnia for those with dementia.
    My husband is early vascular. I recommended it to his primary. He takes it and has wonderful results. His anxiety in AM is also better.
    Maybe due to a good night's sleep.
    Trazadone is old....and cheap. In the USA that's a positive:)
     
  11. Costa fortune

    Costa fortune Registered User

    Mar 10, 2018
    28
    And I love Liquorice lol
     
  12. Carmar

    Carmar Registered User

    Feb 2, 2016
    860
    Female
    Hampshire

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