Quetiapine (seroquel)

blue sea

Registered User
Aug 24, 2005
270
England
Dad has just been prescribed quetiapine (seroquel) as he has recently been very aggressive and has hurt several residents in his home. A consultant psychiatrist has seen him befoe prescribing. So far it is calming him down which means the home can cope with him. I know a recent study suggested this drug accelerated the decline. Doesanyone have any personal experience of this with a relative? I noticed the research was on a very small number of people.

Blue sea
 

McK

Registered User
Sep 13, 2005
62
Pgh. Pa. USA
Seroquel

Dear Blue Sea - My wife, who has alzheimers was put on Seroquel for a time but it wasn't effective, so she was put on Ativan (Lorazepam). It's possible they may have to try out several drugs before hitting it right. You can get all the info you need on Seroquel and most all other drugs by going to : http://www.mentalhealth.com/drug/p30-q01.html. Hope this helps you out - J. McK
 

thompsonsom

Registered User
Jul 4, 2004
97
halifax
Hi Blue Sea

My mum in law was put on this tablet over a year ago and with out it we would not have been able to keep her at home for the 20 months she lived with us, it was a godsend as it calmed her down and made her less aggressive. we have now transfered to a care home where she is so far very happy and is still on the tablet. Take what you can and try it out, thats all you can do, I wouldn't say it progressed the illness any quicker. They did put her on aricept eventually which also helped as she never sundowned after which made life easier for our family.

Hope this helps you


Jan
 

Kriss

Registered User
May 20, 2004
513
Shropshire
Aunt went on Seroquel about 9 months ago and initially she seemed to be totally knocked out by it but after a week or two she seemed to find a level and it worked well.

Sadly the ever changing/deteriorating nature of the illness means that effects don't last for ever. Everyone is different and the results may not be the same for your Dad.

As with any drug the effects will need to be monitored

Kriss
 

blue sea

Registered User
Aug 24, 2005
270
England
Thanks

Thanks for your replies which were very helpful. So far there has been a big improvement in dad. He is much calmer and happier and has had no violent spells since he started on the drug. He has had several falls though (without hurting himself)as though his knees just give way. They are monitoring the dose so hope that will settle down. I know there's always going to be some down side to any medication but I'm so relieved to see him happy again and that the home can cope with him.

Blue sea
 

daughter

Registered User
Mar 16, 2005
824
Hi Blue sea,

Pleased to hear that things have calmed down a little for you and your Dad. Some of our experiences have been similar, although my Dad has (so far) only had one of those dreadful hospital episodes. :mad:

I hope your Dad continues to settle - it's really quite a relief isn't it?

Best wishes,
 

blue sea

Registered User
Aug 24, 2005
270
England
Dad's happier!

The medication is still working really well. Had a lovely visit to dad on Thursday when he was so relaxed and 'chatty'. For weeks he just wouldn't sit still for more than 2 minutes but was constantly walking round the home (fortunately it's got lots of corridors!) and was always anxious, irritable, or actually violent. I feel I've got my dad back to some extent. I know it is only the medication, but at least it has restored his gentle personality, though not of course his mental faculties. Thanks for your support, Hazel, and everyone else. I'll make the most of this better spell as don't know how long it'll last.

Blue sea
 
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susie

Registered User
Nov 30, 2003
82
shropshire
I haven't posted for a while so I was pleased to see this thread as my husband has just been put on quetiapine. He has frontotemporal dementia as well as AD and I have seen him go over the last six months from just being agitated to joking about hitting me and finally landing a full right hook. He was very apologetic when he calmed down and during respite this week, he was put on a very low dose of quetiapine. I've been reading up about it on the net so I think you have to weigh up the pros and cons of the disease being accelerated in exchange for better times together. As they begin the drug they can be very sleepy initially, so at least I can look forward to a quiet time on his return!
Thanks for the experiences.
Susie
 

blue sea

Registered User
Aug 24, 2005
270
England
Yes, dad is very sleepy at the moment, Susie, but the nurses say this will reduce. In any event, better to be asleep than thumping someone! I'm totally against excessive medication to sedate people, but the right level and type of medication can improve behaviour synptoms, at least for a while. I don't kid myself this is a permanent solution. Hope your situation improves too.

Blue sea
 

susie

Registered User
Nov 30, 2003
82
shropshire
David came back from respite very subdued which I think is the initial reaction to the drug. He seems far more relaxed and less anxious. Yesterday I asked him to do something that would normally involved a hostile reaction from him and you could have knocked me down with a feather when he did the job even with a smile! I know the effects of the drug won't last forever but the nurses say he has started on 50 mg and the maximum dosage is 750mg!!! It has brought a little bit of fun back into our relationship which was under strain so I shall enjoy the moment. I almost felt I had the old husband back but then this illness does tease us doesn't it?
Susie
 

blue sea

Registered User
Aug 24, 2005
270
England
Susie
Couldn't agree more with your comments. Howvere transitory the improvement, regaining some of the enjoyable part of the relatoinship is worht every minute.
Dad is still reacting well - is much more relaxed and as you say less anxious.
Blue sea