I''m a Yank, age 65, with early onset, symptoms going back at least 6 years. I have noticed that sometimes things improve from time to time, but always end up back on the same downward progression. Sometimes memory is better, but mood/anxiety etc. are worse, and various other combinations. Is it unusual to have periods of days, weeks, sometimes as long as a month for certain areas to be better while others remain the same, or new ones pop up? I ask at the US forum, but never got a response from anyone who has a solid diagnosis about their personal experience. I also interested in whether the doctors in the UK agree with this type of erratic stuff. Thanks.