Recently my OH developed a skin irritation under his rivastigmine patches, together with a mild rash on his back, and an increase of itchiness of his legs which is a longstanding problem. The consultant advised a week break from them and then restart the lower dose ones, which we have done. Rash has gone though still gets mild reaction actually under the patch. However in the late afternoons he now seems to be feeling unwell, complaining of bad head, sore tummy, as well as itchy legs and generally being quite morose and just sitting doing nothing. Seems to be ok in the earlier part of the day. I am finding it very hard to continue to sympathise, especially in view of the many disagreements I have to try to avoid each day. Has anyone else come across this with this medication, or should I try to discuss it with the consultant again. He was diagnosed in February this year but still cannot see that he has a problem.