My Auntie was diagnosed with AD last year although her symptoms have been around for years as they were confused with complications of drugs that arose from failed operations about 10 years ago intended to cure her Trigeminal neuralgia. Her condition is now deteriorating and my uncle struggles physcologically and increasingly has to do things for her. Their two sons who have left home are not understanding and do not give their dad any support only feel that their mum has gone and that he should leave her! He is therefore coping day to day all alone but cares very much for my auntie. He lives in a remote part of the country with no real close friends to turn to and family all live at least 150 miles away. He does have access to the internet but I feel is too afraid to use sites such as this. He says he no longer has confidence with the doctors! His local GP recommends my auntie starts taking Donepezil but he had asked my mum, an ex nurse, to do some research about it first. So, my question is: Can anyone advise on this type of drug or any that work for AD patients? He realises there is no cure but I feel he is desperate to try different things, as to whether thats good or bad I don't know. Also, we as close family member wounder whether there is any advice that could be given to my uncle about his well being?