Diagnosed 5 yrs ago hubby has deteriorated quite a lot in last six months. He tells me I am nagging all the time and I am sending him mad. Second rant this week, tomorrow he will have forgotten or say 'did I upset you yesterday'. I try so hard to help him and do things that I think will make him happy but as soon as I say no to anything at all, that sets him off. He says I've given him a headache and goes off to bed. I feel so isolated and am now my beginning to feel constantly on edge (which doesn't help). He can be so nasty and it's not the man I have been married to for 50 years. He has all the usual medication but I just dont know what to do next to keep him calm. Our family all live away but one son has visited for 2 days leaving today. Hubby was fine whilst he was here but son hadn't been gone half hour when the mood changed. Due to go away tomorrow for weekend but now he says doesn't want to go as I will nag him all the time! Sorry just wanted to get it off my chest, just a bad day.