1. sunny

    sunny Registered User

    Sep 1, 2006
    598
    I have just come across an article about the biggest breeder of daffodils Jaap Leenen in the Netherlands and was surprised to see the following paragraph:-

    "The roots and the bulbs are very clean, the clean bulbs are necessary to prepare galantamine he said, referring to the substance found in daffodils used to treat Alzheimer's disease."

    It is in fact the drug Reminyl. I just thought this was an interesting titbit.
     
  2. Grannie G

    Grannie G Volunteer Moderator

    Apr 3, 2006
    68,735
    Kent
  3. Skye

    Skye Registered User

    Aug 29, 2006
    17,000
    SW Scotland
    There appears to be some confusion here!:confused:

    Galantamine comes originally from snowdrop bulbs (the latin name for snowdrop is Galanthus nivalis).

    I've read your link, Sylvia, and it definitely states that it comes from daffodils, so perhaps they contain a similar ingredient.:confused:
     
  4. Grannie G

    Grannie G Volunteer Moderator

    Apr 3, 2006
    68,735
    Kent
    Hi Hazel. Are snowdrops from the Narcissus family of bulbs? Perhaps that`s the connection.
     
  5. jenniferpa

    jenniferpa Volunteer Moderator

    Jun 27, 2006
    39,419
    They can also get it from Spider Lilies. I imagine that as daffodils have larger bulbs, it's more economic to use them rather than snowdrops, but why these diverse species have the same compound is beyond me. Perhaps it's a function of being a bulb?
     
  6. Skye

    Skye Registered User

    Aug 29, 2006
    17,000
    SW Scotland
    Quote from Wikipedia

    http://en.wikipedia.org/wiki/Galanthus

    "An active substance in snowdrop is called galantamine, which, as anticholinesterase, could have acted as an antidote to Circe's poisons. Galantamine (or galanthamine) can be helpful in the treatment of Alzheimer's disease, though it is not a cure; the substance also occurs naturally in daffodils and other narcissi."

    Mystery solved!
     
  7. TinaT

    TinaT Registered User

    Sep 27, 2006
    7,095
    Bolton
    How very interesting and what erudite talking point members we are privilaged to have. I often wonder how our ancestors who first used the various plants slowly discovered which worked, at what strength and for what disease. Nature at its most complex and fascinating

    xx TinaT
     
  8. connie

    connie Registered User

    Mar 7, 2004
    9,519
    Frinton-on-Sea
    Thank you ladies. It proves, in my case, "you are never too old to learn"
     
  9. Gromit

    Gromit Registered User

    Apr 3, 2006
    187
    Edinburgh
    Made in edinburgh

    Just thought you might be interested to know that my husband's friend actually is in charge of production (signs off on quality assurance for human consumption!) for guess what.......... yep Reminyl.

    It is produced up here in Edinburgh.

    I'm going to get some information from him on the drug if I can as my Dad has been prescribed it. I hadn't realised that our friend was producing these drugs! Small world eh?

    He works shifts so it may be a few days before I manage to get in touch with him - but I will keep you all posted.

    I'm sure he would have more information on other drugs too - let me know if anyone would like me to ask on their behalf.

    Kind regards

    Alison
     
  10. Skye

    Skye Registered User

    Aug 29, 2006
    17,000
    SW Scotland
    That would be very helpful, Alison. Thank you.
     
  11. Gromit

    Gromit Registered User

    Apr 3, 2006
    187
    Edinburgh
    Some info that might be interesting

    I spoke to my friend last night and found out the following:

    It takes 134 tonnes of daffodil bulbs (which is what they use up here in Edinburgh to produce Reminyl) to produce 37 kilos of ingredient.

    Then 1 kilo of ingredient will produce 20,000 tablets.

    In order for the bulbs to successfully produce Galantamine they have to have suffered a frost. The bulbs therefore that are suitable are only grown in UK, Holland and Belgium.

    Japan has been manufacturing synthetic galantamine however this would be prone to impurities and the UK guidance states that only natural ingredients can be signed off as fit for human consumption.

    Reminyl attacks the enzym that destroys the neurotransmitter (messenger). It also competes with the production of the enzym.

    Aricept increases neurotransmitters.

    Hope the above was of interest.

    If anyone wants to know anymore let me know.

    Alison
     
  12. CraigC

    CraigC Registered User

    Mar 21, 2003
    6,630
    London
    Hi All,

    This is fascinating. I did a bit of research on aricept when it was prescribed to dad. It was overwhelming the amount of research and information on the web. What it taught me is that the drugs prescribed for alzhiemers do not suit everyone and every case is individual and needs constant monitoring. Great to find out more about the sources/manufacturing though.

    I'm always a little nervous about discussing dads medication in case someone reads it as medical advice or takes it too literally. Hence my caveat for the day :)

    The more we learn about these drugs the better in my opinion. And that goes for any prescribed drugs or over the counter drugs.

    Kind Regards
    Craig

    --------------------
    None of the moderators and few group members, are medical professionals. This forum is not meant to substitute professional medical advice. You MUST consult qualified doctors or specialist for diagnosis, treatment, and further advice that is appropriate for you. The information provided through this forum should not be used for diagnosing or treating a health problem or a disease.
     
  13. Skye

    Skye Registered User

    Aug 29, 2006
    17,000
    SW Scotland
    Thanks, Alison, that's very interesting
     
  14. sunny

    sunny Registered User

    Sep 1, 2006
    598
    Thanks

    Alison,
    134 tonnes of daffodil bulbs. "Blooming" heck!
    Great info. I shall look at daffs. with different eyes now. regardsxxxxxx
     
  15. cynron

    cynron Registered User

    Sep 26, 2005
    429
    east sussex
    Some Daffodils

    AROUND OUR VILLAGE SIGN THIS SPRING.

    cCynron X X
     

    Attached Files:

  16. connie

    connie Registered User

    Mar 7, 2004
    9,519
    Frinton-on-Sea
    Dear Cynron, thank you for your very cheery picture of the daffodils. You must always have your camera with you, you have such a keen eye for a photograph.

    Love 'hugs
     
  17. cynron

    cynron Registered User

    Sep 26, 2005
    429
    east sussex
    daffs

    Dear Connie.

    These particular daffs have a place in my heart as my husband and i with others planted them. We also co ordinated the 2000 sign for the village,visiting the blacksmith and accepting the oak post that the Conservators of the forest donated.

    Cynron x x
     

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