I'm normally such a very strong and positive person but I'm worried about myself right now, as well as my Mum, who has lived with me as her sole carer for over 4 years. I have written about my situation before and this year has been just dreadful and so far there is no let up. Two hospital stays this year and apart from obviously having vascular dementia, there appears to be no medical reason Mum is like this. The past 3 weeks especially, Mum is just so aggitated, horrendously so, and I don't know what to do. The GP just says it's a progression of her illness, prescribed an antidepressent Amitriptiline, which she's been on for 12 weeks which hasn't worked. She started a different one yesterday, Mirtazapine, as recommended by the "neighbourhood team" who have recently become involved. However, she was on that 2 years ago and it made her aggressive and she lost her mobility so came off it but they wanted to try it again, (against her GPs recommendation). She always cries a lot, but for 3 weeks solid, as soon as she wakes is crying, wailing, making horrible grunting noises and continually trying to get out of whichever room she is in. If she's in her bedroom she will bang and crash her frame down the landing to the bathroom, sit down, go back to her bedroom then exactly 4.5 seconds later does the same, yes really!! This happens in the morning and also at bedtime and can happen up to 25/30 times. She cannot be distracted and she doesn't know she's doing it. I lock my bedroom door (or she will keep coming in my room) but she will sometimes get up and keep trying my door for up to 2 hours at a time, which is a cottage style latched door so it's click click click all night/morning. When she's downstairs, she will go from door to door clicking the latches or trying to get out in the garden or front door. All the time she is crying and wailing and trawling her blanket behind her. It's heartbreaking, distressing and every emotion you can imagine. I can't bear to see her.like this and I don't think I can cope anymore. I just simply cannot believe, in this day and age there is nobody to help or anything that I can give her to help. I'm on my knees and have exhausted all avenues. I still want to continue to care for my Mum until the end at home with me but at the moment I don't know how to. Everyday I hope she will be less aggitated. I still manage to get her out somewhere everyday and during that time she is like a different person, happy and smiley, but back home its a different story! Even her music dvds do not soothe her anymore. What do I do?