Department of Health £22 Million Funding for Dementia Research Projects

Nessa456

Registered User
Nov 19, 2004
131
0
West Midlands
I'm signed up for email updates from the Department of Health website and just received this information re funding to be made available for Dementia research. The information about the blood pressure drug Losartan is very interesting and all news to me. The telecare stuff is all about cost cutting and ridiculous in terms of how dementia affects a person - most people with dementia past a certain level will not be safe on their own in their home, no matter how good the telecare technology! There's no substitute for proper human care and company, no matter how well they try and sell this telecare concept to people! The plain fact that a person with dementia probably won't be able to operate the technology, understand it or will forget how to do it seems to have eluded the designers!


http://www.dh.gov.uk/health/2012/12/dementia-fund/

Funding made available for dementia research projects

21 December, 2012

The Department of Health has made £22 million available to 21 pioneering research projects to boost dementia diagnosis rates and trial ground-breaking treatments.

Health Secretary Jeremy Hunt emphasised the crucial role of medical research in making breakthroughs in the prevention and treatment of dementia, while ensuring that research can help people with dementia live well with the condition today.

The funding was awarded by the National Institute of Health Research (NIHR) and was designed to cover all areas of scientific activity relevant to dementia, across the fields of care, cure and cause, including prevention.

Some of the projects awarded funding today include:

Trialling the use of the popular blood pressure drug Losartan to complement current treatments for Alzheimer’s Disease. The trial will examine whether the drug improves blood flow to the brain and whether this can alter the chemical pathways that cause brain cell damage, brain shrinkage and memory problems.

The UK’s first ever trial to measure how much longer people with dementia can live safely and independently in their own homes, when they are provided with a specialised telecare technology package including motion sensors, GPS trackers, and personal alarms.

A trial to speed up and improve up diagnosis rates for dementia with Lewy Bodies, which accounts for up to 20 per cent of all cases, yet only one in three are actually diagnosed. The trial aims to produce a comprehensive toolkit for GPs to make spotting the signs of the disease easier and improve diagnosis rates.

Jeremy Hunt said:

“The UK has a firm ambition to become a world leader in dementia research. It is home to some of the world’s best dementia researchers and specialist research facilities, and this Government is committed to supporting them.

“To make a real difference to research, Government must respond to the barriers the industry faces. It is vital that we can translate the excellent work happening in our laboratories across the country into treatments that can help people live well with dementia today, whilst ultimately working towards finding a cure.”

More than 670,000 people in England are currently diagnosed with dementia, and this figure is set to double in the next 30 years, creating one of the biggest challenges faced by the UK in recent times.
 

Nessa456

Registered User
Nov 19, 2004
131
0
West Midlands
These are the 21 Projects to be funded:-

http://www.nihr.ac.uk/files/pdfs/Dementia/Dementia 21 funded projects 20.12.2012.pdf

from the National Institute for Health Research (NIHR) website

http://www.nihr.ac.uk/research/Pages/Dementia.aspx


Efficacy and Mechanism Evaluation (EME) Programme:

EME 11/47/03 Reducing pathology in Alzheimer’s disease through Angiotensin
TaRgeting - The RADAR Trial.

Alzheimer’s disease (AD) profoundly affects memory and brain function in older
individuals. It is a slow progressive disease, which can last for a number of years.
With an ageing population, AD health care provision needs will significantly rise.
Existing treatments only temporarily treat specific imbalances in the brain but as yet,
there is no cure for AD. The team will undertake a multi-centre clinical trial in the UK,
co-ordinated by Bristol, and in collaboration with University College London (UCL)) to
see if losartan, a well-tolerated blood pressure drug, can complement current
treatments for AD. The team believe losartan can slow down the progression of AD
by improving blood flow in the brain and altering chemical pathways that cause brain
cell damage, brain shrinkage and memory problems in AD.


EME 11/47/01 Minocycline in Alzheimer's disease Efficacy Trial: The MADE
Trial.

Although drugs exist that can improve some of the symptoms, there are no
treatments that slow down or stop the progression of dementia. This study will trial
the use of Minocycline, an antibiotic that has shown the potential to protect brain
cells in a number of experimental models of Alzheimer's and other neurological
diseases. 500 patients who are at the earliest stages of Alzheimer’s disease will be
treated for 2 years with minocycline to see if this slows down decline in cognition
and functional ability. Still in contracting stage.
 
Last edited:

TinaT

Registered User
Sep 27, 2006
7,097
0
Costa Blanca Spain
I wonder if a tiny corner of this budget could be used for other dementias such as Lewy Body Disease which is a particularly nasty, horrible disease. There are many diseases under the umberella term of dementia, not just alzheimer disease.

xxTinaT
 

Nessa456

Registered User
Nov 19, 2004
131
0
West Midlands
I wonder if a tiny corner of this budget could be used for other dementias such as Lewy Body Disease which is a particularly nasty, horrible disease. There are many diseases under the umberella term of dementia, not just alzheimer disease.

xxTinaT

It says this in my first post:-

"A trial to speed up and improve up diagnosis rates for dementia with Lewy Bodies, which accounts for up to 20 per cent of all cases, yet only one in three are actually diagnosed. The trial aims to produce a comprehensive toolkit for GPs to make spotting the signs of the disease easier and improve diagnosis rates."

I am very interested in the extent to which people read information which is posted online. Did you see the above information in my post or did you see it as not relevant?
 

SueShell

Registered User
Sep 13, 2012
395
0
Orpington
Well that's interesting because my Mum has been on Losartan for high blood pressure for years and years and she's got AZ!
 

TinaT

Registered User
Sep 27, 2006
7,097
0
Costa Blanca Spain
A trial to speed up and improve up diagnosis rates for dementia with Lewy Bodies, which accounts for up to 20 per cent of all cases, yet only one in three are actually diagnosed. The trial aims to produce a comprehensive toolkit for GPs to make spotting the signs of the disease easier and improve diagnosis rates.

Sorry I've re read and found the above. I speed read and read Az so many times in the article I missed the reference to LBD

xxTinaT
 

aeon456

Account Closed
Mar 12, 2011
58
0
Wolverhampton
Well that's interesting because my Mum has been on Losartan for high blood pressure for years and years and she's got AZ!

I think the main thing is that high blood pressure is linked to Alzheimers and Losartan is one of the newer types of high blood pressure drugs that is more effective, hence in studies people taking it have been found to be less likely to have Alzheimers than people on other HBP drugs and people not on a HBP drug, presumably because their high blood pressure is being kept under better control. But I think they don't understand the mechanism of how it all works at the moment, hence the need for more research.

Can I ask how old your Mother is, when was she diagnosed with Alzheimers and do you know what stage of the condition she is at?
 
Last edited:

aeon456

Account Closed
Mar 12, 2011
58
0
Wolverhampton
A trial to speed up and improve up diagnosis rates for dementia with Lewy Bodies, which accounts for up to 20 per cent of all cases, yet only one in three are actually diagnosed. The trial aims to produce a comprehensive toolkit for GPs to make spotting the signs of the disease easier and improve diagnosis rates.

Sorry I've re read and found the above. I speed read and read Az so many times in the article I missed the reference to LBD

xxTinaT

Ok, I just wasn't sure if you'd seen that bit or not :)

I seem to have 2 ID's on here - I am Nessa456 as well as aeon456 btw
 
Last edited: