My father's consultant - having never met him! - has decided, in their infinite wisdom, that Daddy should change from Aricept to Memantine.
From what I have read on the Internet, there was a trial in 2008, yes, 2008, and a paper published which clearly stated that people who have been stable on Aricept for some time and then added Memantine into the mix then had a therapy which slowed cognitive and functional decline in Alzheimer's compared with Aricept on its on or no drug treatment. The benefits had small-to-medium effect sizes that increased with time on treatment and were sustained for years.
Well that sounds good and yet, even though this study is now quite old in medicine terms, NICE haven't included it in their latest studies - why, what are these people paid for exactly? Now that Aricept has lost its unique licence and can be made by other pharmaceutical companies, it will have become cheaper so what would be the problem in hoping for the best outcome and going with the combination therapy, just in case it works, but why do I think I am going to have the devil of all battles trying to get any help with this from the consultant?
I can't even access a copy of the study without paying over $300 to the American publishers, and I want a copy of that so that I have something to show them when it comes to any discussion on the subject.
So, has anyone got the combination therapy in place and, if so, how did you get it?